OphiDx® is a data management, analyses and clinical reporting platform for clinical genetics/genomics laboratories, developed by our bioinformatics team to support the implementation of a data-driven precision medicine laboratory pipeline. OphiDx has been under use and constant development for over three years.

dados  Data aggregation

One platform – any technology – Integration in a single platform of results from multiple molecular testing technologies: NGS, Sanger, MLPA®, PCR, qPCR, dPCR, etc., enabling the integrated analysis and reporting of all the results for each patient.

Integration with scientific data– Local and automated integration of results with up to date versions of the most relevant international databases of variants and their molecular consequences,  bioinformatics algorithms, relevant clinical trials, population data, relevant international guidelines, recent scientific literature, etc.

Integration of clinical data – All the data for each patient is  integrated, enabling a comprehensive view of the patient and enabling a better informed interpretation of laboratory results.

intel Computational intelligence

Decision support – A bioinformatics pipeline for variant/alteration annotation and pre-interpretation of the clinical impact based on multiple data sources with structured presentation to facilitate analysis and decision by the specialist.

Clinical grade automated reporting – Automated production of customisable clinical reports, enabling full or semi-automated completion of the report;  for semi-automated, human expert assisted reporting, pre-filled reports with suggested text simplifies and expedites report production.

Structured results – Information is organised so as to simplify the work of the clinicans, with clear, concise and pertinent data to support clinical decision; detailed description of results, methodological information and interpretation is also presented, separately, enabling patient and clinician to discuss in depth the results when so desired.

Re-classification of variants – Every six months all variants for all patients in the lab’s database are reclassified according to the latest scientific data available, enabling the laboratory to alert the clinician when there is any new information that is pertinent to one or more of his/her patients.

qual Quality

Variant history for consistent reporting – The full history of the lab’s processing of any  variant/alteration is kept in the system, and becomes automatically available for interpretation and clinical reporting.

Similar patients – The system automatically recognises similarities between patients ,  increasing consistency in reporting and facilitating clinical insight.

opti Laboratory optimisation

HL7 integration – The adoption of  Health Level-7 (HL-7) standard facilitates integration and communication with Electronic Medical Record systems, as well as with external laboratory management systems.

From patient to report – The state of completion of each sample can be followed from the point of arrival in the lab to the reporting, enabling the identification of bottlenecks, enabling optimisation of laboratory flows to improve speed and quality.

Laboratory management – A dashboard displaying all samples available for testing, the deadline for reporting, time for testing to respect pre-defined deadlines, availability of equipments, NGS chip optimisation, etc. enable a smooth running of a clinical genomics pipeline. Additional dashboards enable tracking times per technique, per disease context, operator, etc.