Building a better future for cancer patients
Developing tools for early cancer detection and selection of the best curative treatments.

Ophiomics- Precision Medicine

Ophiomics is an ISO 13485 and ISO 9001 certified, clinical-stage Medtech company developing cutting-edge diagnostic products and services integrating bioinformatics, artificial intelligence and genomics in support of diagnostic, prognostic, treatment selection and clinical follow-up in oncology.



We are committed to revolutionizing cancer diagnostics worldwide by leveraging the power of AI-driven IVD tests. We’re forging close partnerships with clinicians to develop a cutting-edge portfolio of technology-driven, cost-effective products with a massive global impact, significantly enhancing health outcomes. Our vision: to lead the world in cancer diagnostics and transform the future of healthcare.


We create practical tools to empower clinicians’ decisions at crucial stages in the cancer patient journey, where preventative or curative interventions are possible.


We leverage the power of genomics and Machine Learning to discover novel biomarkers that address unmet clinical needs.


We integrate biomarkers and clinical variables through cutting-edge machine-learning algorithms, creating solutions to support clinicians’ decisions.


Our end-products – IVD medical devices – are designed to seamlessly integrate into routine clinical practice, ensuring accessibility and ease of adoption


We value partnerships with clinicians, academia, patients, and companies, to build upon and advance our approaches, seeking improved outcomes for all.

Jose Leal, PhD (CEO)

José Pereira Leal, PhD, is a bioinformatician with close to 30 years professional experience. Dr. José Pereira-Leal has a PhD in Biomedical Sciences from the University of Oporto (Portugal), having performed all the thesis research work at the Imperial College School o Medicine (London, UK) and the Souwestern Medical School at Dallas (Texas, USA). His PhD thesis focused on the biochemistry and bioinformatics of proteins involved in genetic diseases.

Joana Vaz, PhD (CSO)

Joana Cardoso Vaz, PhD, is a specialist in cancer Genomics, with ample experience collaborating with clinicians, from biomarker discovery to clinical diagnosis. Dr. Joana Cardoso Vaz has an MSc in Human Genetics from the School of Medicine of the University of Lisbon (Portugal), and a PhD in Biomedical Sciences from the University of Leiden (Netherlands). During her PhD research she specialised in cancer genomics, with a focus on colo-rectal cancer. As a post doctoral fellow she worked at the Instituto de Medicina Molecular and at the Instituto Gulbenkian de Ciência using genomics technologies (NGS, microarrays, qPCR) to study mechanism and markers of cancer progression (Breast, Liver and Oesophageal Cancer).

José Leal
Joana Vaz
Sandra Joanes
Germano de Sousa

Christophe Duvoux

Hepatology - FR

Marina Berenger

Hepatology - ES

Hugo Pinto Marques

HepatoBiliary Surgery - PT

Susana Mão de Ferro

GastroEnterology - PT

Ana Sofia Carvalho

Ethics - PT

Jean-Pierre Hermet

In Vitro Diagnostics - FR

Postal address (Headquarters):

Pólo Tecnológico de Lisboa, Rua Cupertino de Miranda, 9 – Lote 8, 1600-513 – Lisboa

Lab address:

Pólo Tecnológico de Lisboa, Rua António Champalimaud, Lote 1 (sala 14), 1600-514 – Lisboa

Tlf.: +351 211 369 829